Madurella Fahalii

 

Etymology:

Named after Ahmed Fahal, mycetoma expert and founder of the Mycetoma Research Centre in Khartoum, Sudan.

Morphological Description:

The growth rate of M. fahalii CBS 129176 was low; the colony reached a diameter of 26 mm after 2 weeks at 37°C. Colonies were flat and gray-brown (Fig. A). No diffusible pigment was produced on SGA. Microscopically, numerous chlamydospores were observed, in addition to brownish hyphae (Fig. B). Chlamydospores were subglobose, thick-walled, about 10mm in diameter, and intercalary or terminal. No conidia were detected. The fungus showed optimal growth at 30°C; at this temperature, the colony reached a diameter of 29 mm.

Molecular Identification:

ITS sequencing is recommended.

Phylogeny:

The amplified ITS region of M. fahalii CBS 129176 was 595 bp long (GenBank accession number JN573178) and shared 91.9% identity with that of the type strain of M. pseudomycetomatis (TMMU 3956) (GenBank accession number EU815933.1).

In vitro antifungal activity

In vitro susceptiblity of Madurella fahalli

 

References:

de Hoog GS, van Diepeningen AD, Mahgoub el-S, van de Sande WW. New species of Madurella, causative agents of black-grain mycetoma. J Clin Microbiol. 2012; 50(3):988-994.