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  • Mycetoma Clinicopathological Monograph.
    Prof. Ahmed Hassan Fahal, MBBS, FRCS, MD, MS.
     
     

          José Antonio Serrano
          Ángel Horacio Sandoval
          Blaine L. Beaman
         
Click to download pdf Actinomicetoma

 

          Dr.   WW van de Sande
          Department of Medical Microbiology
          and Infectious Diseases, Erasmus Medical Center
          Rotterdam University

  •   
     
 

 

Publications

 

Fahal AH, Hassan MA. Mycetoma. British Journal of Surgery. 1992; 79(11): 1138-1141. PMID: 1467883.

Fahal AH, Suliman SH, Gadir AFA, EL Hag IA, EL Amin FI, Gumaa SA, Mahgoub ES. Abdominal wall mycetoma: an unusual presentation. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1994; 88: 78-80. PMID: 8154012.

Fahal AH, Suliman SH. Clinical presentation of mycetoma. Sudan Medical Journal. 1994; 32: 46-66. 

Fahal AH, EL Toum EA, EL Hassan AM, Gumaa SA, Mahgoub ES. A preliminary study on the ultrastructure of Actinomadura pelletieri and its host tissue reaction. Journal of Medical and Veterinary Mycology. 1994; 32: 343-348. PMID: 7844700.

EL Hassan AM, Fahal AH, EL Hag IA, Khalil EAG. The pathology of mycetoma: Light microscopic and ultrastructural features. Sudan Medical Journal. 1994; 32: 23-45. 80036

Fahal AH, Hassan MA, Sanhouri M. Surgical treatment of mycetoma. Sudan Medical Journal. 1994; 32: 98-104

Fahal AH, EL Toum EA, EL Hassan AM, Gumaa SA, Mahgoub ES. Host tissue reaction to Madurella mycetomatis: New classification. Journal of Medical and Veterinary Mycology. 1995; 33: 15-17. PMID: 7650573.

EL Hag IA, Fahal AH, Khalil EAG. Fine needle aspiration cytology of mycetoma. Acta Cytologica. 1996; 40(3): 461-464. PMID: 8669179.

Fahal AH, Omer SM, El Razig SA, Ali ABE, Mahdi EMA, Mahgoub ES. Thyroid function in mycetoma patients. East African Medical Journal. 1995; 72(7): 454-456. PMID: 7498029.

Fahal AH, Azziz KAA, Suliman SH, Galib HV, Mahgoub ES. Dual infection with mycetoma and tuberculosis. East African Medical Journal. 1995; 72(11): 749-750. PMID: 8904072.

Mohamed ARO, Fahal AH, Venge V. Immunoglobulin and inflammatory markers profile in mycetoma. East African Medial Journal. 1996; 73(4): 212 (Letter). PMID: 8698027.

Fahal AH, Yagi HI, EL Hassan AM. Mycetoma induced palatal deficiency and pharyngeal plexus dysfunction. Transactions of Tropical Medicine and Hygiene - 1996; 90: 676-677. PMID: 9015514.

Fahal AH, Sheikh HE, EL Hassan AM. Pathological fracture in mycetoma. Transactions of Tropical Medicine and Hygiene - 1996; 90: 675-676. PMID: 9015513.

Fahal AH, Sharfi AR, Sheikh HE, EL Hassan AM. Mycetoma: Uncommon complication. Transactions of Tropical Medicine and Hygiene. 1996; 89: 550-552

Fahal AH, Sadig ME, Suliman SH, EL Razig SA, Mahgoub ES. Lack of association between ABO blood groups and Rh factor and the tendency to develop mycetoma. East African Medical Journal - 1996; 11: 769. (Letter). PMID: 8997873.

Fahal, AH, EL Hag IA, Gadir AFA, EL Lider AR, Baraka OZ, EL Hassan AM. The blood supply and vasculature in mycetoma. Journal of Medical and Veterinary Mycology - 1997; 35: 101-106. PMID: 9147269.

Fahal AH, Sheikh HE, EL Lider MA, Homeida MA, EL Arabi YE, Mahgoub ES. Ultrasonic imaging in mycetoma. British Journal of Surgery – 1997; 78: 765-766. PMID: 9278658.

Fahal AH, Sharfy ARA. Vulval mycetoma: a rare cause of bladder outlet obstruction. Transactions of Tropical Medicine and Hygiene. 1998; 92: 652-653. PMID: 10326112.

Ahmed AO, Mukhtar MM, Kools-Sijmons M, Fahal AH, de Hoog S, van den Ende BG, Zijstara, ED, Verburgh H, Abugroun ESA, EL Hassan AM, van Beklkum A. Development of a species-specific PCR RFLP procedure for the identification of Madurella mycetomatis. Journal of Clinical Microbiology. 1999; 37(10):3175-8. PMID: 10488173. [Download Free Article]

Fahal AH. The management of mycetoma. Post-Graduate-Caribbean. 2000;16(4):229-232.

EL Hassan AM, Fahal AH, Ahmed AO, Ismail A, Veress B. The immunopathology of actinomycetoma lesions caused by Streptomyces somaliensis. Transactions of Tropical Medicine and Hygiene- 2001: 95(1); 89-92. PMID: 11280076.

Ahmed AOA, Adelmann D, Fahal AH, Verbrugh HA, Van Belkum A, De Hoog S. Environmental occurrence of Madurella mycetomatis, major agent of human eumycetoma in Sudan. Journal of Clinical Microbiology. 2002 40(3): 1031-1036. PMID: 11880433. [Download Free Article]

Ahmed AOA, van Vianen W, ten Kate M, van de Sande WWJ, Van Belkum A, Fahal AH, Verbrugh HA, Bakker- Woudenberg IAJM. A murine model of Madurella mycetomatis eumycetoma. FEMS immunology and Medical Microbiology – 2003; 37: 29-36. PMID: 12770757. [Download Free Article].

Ahmed AOA, van de Sande W, Van Belkum A, Verbrugh HA, Fahal A H, van Belkum A. Madurella mycetomatis strains from mycetoma lesions in Sudanese patients are clonal. Journal of clininical microbiology. 2003; 41(10):4537-41. PMID: 14532179. [Download free article]

Abd Bagi ME, Fahal AH, Sheik HE, Abdul Wahab O, Taifoor MK, Osmanr EM. High incidence of pathological fracture in mycetoma. Transactions of Tropical Medicine and Hygiene 2003; 97(5):582-4. PMID: 15307432

Fahal AH. Mycetoma thorn on the flesh Review article. Transactions of Tropical Medicine and Hygiene- 2004; 98(1):3-11. Review. PMID: 14702833

Ahmed AO, van de Sande WW, van Vianen W, van Belkum A, Fahal AH, Verbrugh HA, Bakker-Woudenberg IA.In vitro susceptibilities of Madurella mycetomatis to itraconazole and amphotericin B assessed by a modified NCCLS method and a viability-based 2,3-Bis(2-methoxy-4-nitro-5- sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium hydroxide (XTT) assay. Antimicrob Agents Chemother. 2004; 48(7):2742-6. PMID: 15215141. [Download Free Article].

Ahmed AO, van Leeuwen W, Fahal A, van de Sande W, Verbrugh H, van Belkum A. Mycetoma caused by Madurella mycetomatis: a neglected infectious burden. Lancet Infectious Diseases. 2004; 4(9):566-74. Review. PMID: 15336224.

EL Hassan AM, Fahal AH, Veress B. Cell phenotypes, immunoglobulins, and complement in lesion of eumycetoma caused by Madurella mycetomatis. Sud J Dermato 2006; 4 (1):2-5.

van de Sande WW, Fahal A, Verbrugh H, van Belkum A. Polymorphisms in genes involved in innate immunity predispose toward mycetoma susceptibility. J Immunol. 2007; 179(5):3065-74. PMID: 17709521. [Download Free Article].

van de Sande WW, de Kat J, Coppens J, Ahmed AO, Fahal A, Verbrugh H, van Belkum A. Melanin biosynthesis in Madurella mycetomatis and its effect on susceptibility to itraconazole and ketoconazole. Microbes Infect. 2007; 9: 1114-1123. PMID: 17644456.

van de Sande WW, Fahal A, Verbrugh H, van Belkum A. Madurella mycetomatis compounds cross-reactive with galactomannan are detectable in culture supernatant but not in serum. J Med Microbiol. 2007;56: 869-70. PMID: 17510278. [Download Free Article].

Ahmed AA, van de Sande WW, Fahal A, Bakker-Woudenberg I, Verbrugh H, van Belkum A. Management of mycetoma: major challenge in tropical mycoses with limited international recognition. Curr Opin Infect Dis. 2007; 20(2):146-51. PMID: 17496572.

van de Sande WW, Fahal AH, Riley TV, Verbrugh H, van Belkum A. In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin. J Antimicrob Chemother. 2007; 59(3):553-5. PMID: 17324961. [Download Free Article].

Hussein A, Ahmed AEM, Fahal AH, Mahmoud A, Sidig A. Awad K, Ahmed EM. Cervical cord compression secondary to mycetoma infection. Sud J Pub Health. 2007; 2(2): 112-115.

Quintana ET, Wierzbicka K, Mackiewicz P, Osman A, Fahal AH, Hamid ME, Zakrzewska-Czerwinska J, Maldonado LA, Goodfellow M. Streptomyces sudanensis sp. nov., a new pathogen isolated from patients with actinomycetoma. Antonie Van Leeuwenhoek. 2008; 93(3):305-13. PMID: 18157699.

71. Dejan Stojković, Marina Soković, Ana Džamić, Mihailo Ristić, Ahmed Fahal Silvana Petrović, Ivana Djujić Sami Khalid. In vitro Susceptibility of Actinomadura madurae Clinical Isolates to Turpentine Oil of Pinus pinaster and α-Pinene. Arch. Biol. Sci., Belgrade. 2008; 60 (4): 697-701.

Abd El-Bagi MEB, Fahal AH. Mycetoma revisited. Incidence of various radiographic signs. Saudi Med J. 2009;30(4):529-33. PMID: 19370281.

Yousif BM, Fahal AH, Yahia MY. The Cell Block Technique: A New Diagnostic Tool for Myeloma. Transactions of the Royal Society of Tropical Medicine & Hygiene. 2010; 104(1):6-9.

Fahal AH, Abu Sabaa. AH. Mycetoma in Children. Transactions of the Royal Society of Tropical Medicine & Hygiene. 2010; 104: 117–12. PMID: 19716573.

Fahal, AH. Management of mycetoma. Expert Review of Dermatology. 2010; 5(1), 87–93. art00012

van de Sande WWJ, Fahal AH, Tavakol M, van Belkum A, Polymorphisms in catechol-O-methyltransferase and cytochrome p450 subfamily 19 genes predispose towards Madurella mycetomatis-induced mycetoma susceptibility, (Med Mycol - Accepted). PMID: 20184498

Fahal AH, Rahman I A, El-Hassan AM, Zijlstra EE. The efficacy of itraconazole in the treatment of patients with eumycetoma due to Madurella mycetomatis (In press)

Sengupta M, Hamid ME, Fahal AH, Quintana ET, Goodfellow M. Five new Streptomyces species that encompass strains isolated from mycetoma patients in the Sudan: Streptomyces huangii sp. nov., Streptomyces khartoumensis sp. nov., Streptomyces mahgoubii sp. nov., Streptomyces nyalensis sp. nov and Streptomyces zhihengliuii sp. nov.( Antonie Van Leeuwenhoek - Accepted). PMID: 18157699

Van de Sande, WWJ, Fahal AH, Bakker-Woudenberg IA, Van Belkum A. 2009. Madurella mycetomatis is not susceptible to the echinocandin class of antifungal agents. (Antimicrob Agents Chemother – Submitted). 2010. PMID: 20350944

Fahal AH, EL Sheik H, El Hassan AM. Venous Varicosity In Mycetoma (In press)

de Klerk, N., C. de Vogel, A. van Belkum, and W. van de Sande, Fahal, AH. Gycolytic proteins of Madurella mycetomatis are immunogens in mycetoma. (infect immun manuscript in preparation).

 

 

Contribution to Books & Publications

1.      Fahal AH, Mycetoma: Clinico-pathological monograph, University of Khartoum Press. 2006

2.      Fahal AH, Actinomycetoma in Africa: in Serrano JA, Sandoval AH, Veaman BL, Actinomicetoma,, 2006

3.      Hassan MA, Fahal, AH, Mycetoma: in Tropical surgery book, 2005

4.      Fahal AH, Evidence based guidelines for the management of mycetoma patients, 2001

5.      Editor, Mycetoma in Sudan, Sudan Medical Journal, Supplement, 1994

 

  

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